Skip to main content
ACG 2025 Annual Meeting Main banner
Icon Legend
This session is not in your Favorites.
This session is in your Favorites. Click again to remove it.
Presentation Icons
ACG Award Winner
ACG Award Winner
ACG Newsworthy Abstract
ACG Newsworthy Abstract
Registration Required
Registration Required
No CME
No CME
On-Demand Video
On-Demand Video
Livestream
Livestream

Monday Poster Session

Category: Biliary/Pancreas

P2145 - Ten-Year Cumulative Incidence of Pancreatic Cancers Among the Patients With Branch-Duct Intraductal Papillary Mucinous Neoplasms

Monday, October 27, 2025
10:30 AM - 4:00 PM MT
Location: Exhibit Hall
HyoungChul Oh, 1, Tae Young Park, 1, Junyeol Kim, 2, Jae Hyuk Do, 1, Yoo Shin Choi, 1, Seung Eun Lee, 1, Hyun Kang, 1
1Chung-Ang University Hospital, Seoul, Seoul-t'ukpyolsi, Republic of Korea; 2Chung-Ang University Hospital, Gwangmyeong, Kyonggi-do, Republic of Korea

Introduction: The incidence of pancreatic cancer in patients with branch-duct intraductal papillary mucinous neoplasm (BD-IPMNs) have not been fully evaluated. This study aimed to analyze the incidence of pancreatic cancer among patients with BD-IPMN.

Methods: We identified 321consecutive patients with a diagnosis of BD-IPMN from 2008 through 2021. Age, sex, serum CA 19-9 level, location of BD-IPMN, number of IPMN, size of IPMN, diameter of main pancreatic duct were collected using medical records.

Results: Demographic characteristics were as follows: mean age of 66.0 ± 11.3; 158 male (49.1%) and 162 female patients (50.3%). Of 321 BD-IPMN patients, 101 patients were followed-up over 5 years. The BD-IPMNs were located at the head in 49 (48.5%), body in 15 (14.9%), tail in 12 (11.9%), and multifocal in 25 patients (24.8%). Single neoplasm was observed in 68 patients (67.3%), 2-5 neoplasms in 28 (27.7%), ≥ 6 neoplasms in 5 (5.0%). Sizes were < 10mm in 8 patients (7.9%), 10-19 mm in 47 (46.5%), 20-29 mm in 35 (34.7%), and ≤ 30mm in 11 (10.9%). Median diameter of main pancreatic duct was 3.0 mm (range, 1.0-11.0). Pancreatic cancer developed in 8 patients (IPMN-derived, n=4; De novo, n=4). Five-year incidence and 10-year cumulative incidence of pancreatic cancer were HR 2.72 (CI: 0.182 – 5.252) and HR 10.270 (CI: 2.221 -18.320), respectively.

Discussion: The cumulative incidence of pancreatic cancer among patients with BD-IPMN was gradually increased. Continuous surveillance for the development of pancreatic cancer is necessary.

Disclosures:
HyoungChul Oh indicated no relevant financial relationships.
Tae Young Park indicated no relevant financial relationships.
Junyeol Kim indicated no relevant financial relationships.
Jae Hyuk Do indicated no relevant financial relationships.
Yoo Shin Choi indicated no relevant financial relationships.
Seung Eun Lee indicated no relevant financial relationships.
Hyun Kang indicated no relevant financial relationships.

HyoungChul Oh, 1, Tae Young Park, 1, Junyeol Kim, 2, Jae Hyuk Do, 1, Yoo Shin Choi, 1, Seung Eun Lee, 1, Hyun Kang, 1. P2145 - Ten-Year Cumulative Incidence of Pancreatic Cancers Among the Patients With Branch-Duct Intraductal Papillary Mucinous Neoplasms, ACG 2025 Annual Scientific Meeting Abstracts. Phoenix, AZ: American College of Gastroenterology.