Razan Aburumman, MD, Tala Al Saleh, MD, Syed-Mohammed Jafri, MD Henry Ford Health, Detroit, MI Introduction: Hepatitis A and B are preventable infectious diseases, yet disparities in vaccine uptake persist across demographic groups. This study examines gender and racial/ethnic differences in vaccination rates using NHANES 2017–2020 data. Methods: This study utilized publicly available data from the National Health and Nutrition Examination Survey (NHANES) for the cycles spanning 2017 to 2020. Hepatitis A and B vaccination status was determined through self-reported responses to survey questions regarding prior receipt of these vaccines. Demographic variables, including race/ethnicity (categorized as Non-Hispanic White, Non-Hispanic Black, Hispanic, Asian, and Other) and gender (male or female), were used to assess disparities in vaccine uptake. Descriptive statistics were computed to summarize vaccination rates across demographic groups. SPSS version 26.0 was used to compare vaccination across different groups. Results: A total of 9,693 participants were included in the study, 51.3% of whom were female. The mean age was 50 years (SD = 19), with ages ranging from 18 to 80. Most participants were non-Hispanic White (34.8%) and born in the U.S. (71.7%). Only 27.5% had received at least three doses of the Hepatitis B vaccine, and 23.5% had received at least two doses of the Hepatitis A vaccine. Of those who received at least one dose of Hepatitis A, 72% also received at least one dose of Hepatitis B (p = 0.00). The mean age for Hepatitis A and B vaccine recipients was younger (41.9 and 40.2, respectively) than for non-recipients (52.5 and 53.9, respectively; p = 0.00).
Females were more likely than males to receive at least one dose of both vaccines (Hepatitis A: 28.3% vs. 25.8%, p = 0.007; Hepatitis B: 35.7% vs. 26.2%, p = 0.00). People born outside the U.S. were more likely to receive the Hepatitis A vaccine (31.2% vs. 25.5%, p = 0.00), but no difference was found for Hepatitis B (p = 0.41). Racial differences were significant (p = 0.00), with Asian populations having the highest vaccination rates (Hepatitis A: 37.5%, Hepatitis B: 42.1%) and non-Hispanic Whites the lowest for Hepatitis A (22.7%), and Mexican Americans the lowest for Hepatitis B (25.5%). Discussion: Findings reveal significant disparities in Hepatitis A and B vaccination, particularly by gender and race/ethnicity. These gaps highlight the need for targeted public health interventions to improve vaccine equity.
Disclosures: Razan Aburumman indicated no relevant financial relationships. Tala Al Saleh indicated no relevant financial relationships. Syed-Mohammed Jafri: Abbvie – Speakers Bureau. Gilead – Speakers Bureau. Intercept – Speakers Bureau. Ironwood – Speakers Bureau. Takeda – Speakers Bureau.
Razan Aburumman, MD, Tala Al Saleh, MD, Syed-Mohammed Jafri, MD. P5588 - How Race and Gender Influence Hepatitis A and B Vaccination Rates, ACG 2025 Annual Scientific Meeting Abstracts. Phoenix, AZ: American College of Gastroenterology.
