P0305 - Unmasking the Patterns: Racial and Gender Disparities in Eosinophilic Colitis - Insights from the HCUP National Database (2019-2023)

Sunday, October 26, 2025

3:30 PM - 7:00 PM MT

Location: Exhibit Hall

Presenting Author(s)

Sai Reshma Magam, MD (she/her/hers)

Nassau University Medical Center
East Meadow, New York

Rajmohan Rammohan, MD¹, Dilman Natt, MD¹, Sai Reshma Magam, MD¹, Achal Patel, MD¹, Leeza E. Pannikodu, MD¹, Wing Hang Lau, DO¹, Sindhuja Giridharan, MD¹, Sri Harsha Boppana, MD¹, Venkata Panchagnula, MD¹, Amilcar Guaschino, MD¹, Cesar Orlando Ortiz Bernard, MD¹, Amina Zafar, MD¹, Melvin Joy, MD², Krina Patel, ³, Krishnaiyer Subramani, MD¹, Paul Mustacchia, MD¹
1Nassau University Medical Center, East Meadow, NY; 2HCA Healthcare Citrus Hospital, Inverness, FL; 3The wardlaw Hartridge school, Edison, NJ

Introduction:

This study uses HCUP data (2019–2023) to examine racial and gender disparities in eosinophilic colitis among 2.7 million adult admissions. Findings aim to clarify how these factors influence incidence and guide improved diagnosis and management strategies.

Methods: We analyzed data from the Healthcare Cost and Utilization Project (HCUP) National Database, covering 2,748,576 adult hospital admissions from 2019 to 2023 with a primary diagnosis of Eosinophilic colitis. The initial analysis involved reviewing the dataset's structure, focusing on race, gender, and indicators of eosinophilic colitis. We summarized incidence rates by demographic factors and conducted chi-square tests to detect significant differences in incidence across various racial and gender groups. This involved using contingency tables to provide statistics and calculate p-values. Subsequently, logistic regression was employed to examine the relationships between race and gender as predictors and eosinophilic colitis as the dependent variable.

Results:

From 2019 to 2023, among the 2,748,576 patients admitted, we focused on 10,211 patients with Eosinophilic colitis after performing propensity score matching. The logistic regression analysis revealed significant disparities in the incidence of Eosinophilic colitis based on race and gender. Whites were found to have the highest likelihood of developing the condition (coefficient: 2.2411, p < 0.0001), followed by Blacks (coefficient: 1.0911, p < 0.0001), while Other Races showed a decreased likelihood (coefficient: -1.0702, p < 0.0001). There was no significant difference for Hispanics (coefficient: -0.0102, p = 0.9742). Additionally, males were less likely than females to develop the condition (coefficient: -0.1760, p < 0.0001), highlighting the significant impact of race and gender on the prevalence of the disease.

Discussion: Analysis of the HCUP National Database revealed racial and gender disparities in eosinophilic colitis incidence, highlighting the interplay of genetics, environment, and healthcare access. Higher rates among white and Black populations suggest potential genetic or environmental influences, while lower incidence in males and Hispanics calls for further investigation. These findings emphasize the need for targeted interventions and tailored healthcare strategies to better manage eosinophilic colitis in diverse populations.

Figure: Figure 1

Disclosures:
Rajmohan Rammohan indicated no relevant financial relationships.
Dilman Natt indicated no relevant financial relationships.
Sai Reshma Magam indicated no relevant financial relationships.
Achal Patel indicated no relevant financial relationships.
Leeza Pannikodu indicated no relevant financial relationships.
Wing Hang Lau indicated no relevant financial relationships.
Sindhuja Giridharan indicated no relevant financial relationships.
Sri Harsha Boppana indicated no relevant financial relationships.
Venkata Panchagnula indicated no relevant financial relationships.
Amilcar Guaschino indicated no relevant financial relationships.
Cesar Orlando Ortiz Bernard indicated no relevant financial relationships.
Amina Zafar indicated no relevant financial relationships.
Melvin Joy indicated no relevant financial relationships.
Krina Patel indicated no relevant financial relationships.
Krishnaiyer Subramani indicated no relevant financial relationships.
Paul Mustacchia indicated no relevant financial relationships.

Rajmohan Rammohan, MD¹, Dilman Natt, MD¹, Sai Reshma Magam, MD¹, Achal Patel, MD¹, Leeza E. Pannikodu, MD¹, Wing Hang Lau, DO¹, Sindhuja Giridharan, MD¹, Sri Harsha Boppana, MD¹, Venkata Panchagnula, MD¹, Amilcar Guaschino, MD¹, Cesar Orlando Ortiz Bernard, MD¹, Amina Zafar, MD¹, Melvin Joy, MD², Krina Patel, ³, Krishnaiyer Subramani, MD¹, Paul Mustacchia, MD¹. P0305 - Unmasking the Patterns: Racial and Gender Disparities in Eosinophilic Colitis - Insights from the HCUP National Database (2019-2023), ACG 2025 Annual Scientific Meeting Abstracts. Phoenix, AZ: American College of Gastroenterology.