Professor of Medicine
Mayo Clinic Rochester, MN
Rochester, MN
Manal F. Abdelmalek, MD, MPH, FACG, is a Professor of Medicine, Director of the MASLD Clinical Research Program at Mayo Clinic, Rochester, MN. For the past 25 years, her clinical and research area of interest has focused on metabolic associated steatotic liver disease, its associated risk factors for disease acquisition and progression and the discovery of novel approaches to treatment. She has expertise in clinical-translational research, the design and conduct of clinical trials, including investigator-initiated, industry sponsored and NIH-funded clinical studies evaluating new therapies and biomarkers for MASLD and metabolic associated steatohepatitis (MASH). She collaborates extensively to transition new compounds to first-in-man clinical studies and translate clinic-to-bench and bench-to-clinic research to define pathogenic mechanisms underlying MASLD acquisition and progression. Dr. Abdelmalek is a key opinion leader in the field of MASH therapeutics, a member of the Liver Forum, and advisor/ consultant to many industries, FDA, and biomarker development companies in the area of diagnostics and therapeutics for MASH. She is the lead Principal Investigator on several multicenter global studies, a member of the AASLD Global Outreach and Engagement Committee and past member of the AASLD Clinical Research Committee. As a teacher and educator, she has mentored clinical residents, fellows, and faculty at rank of Assistant / Associate Professor in the study and research of liver disease. Dr. Abdelmalek is a Fellow of ACG, ACP, and AASLD. She is a steering committee member of the NIH Liver Cirrhosis Network and a former 16-year member NASH Clinical Research Network (NASH CRN). Dr. Abdelmalek has published more than 200 manuscripts and currently serves as an Associate Editor of HEPATOLOGY, the official journal of the AASLD.
MASLD and Therapeutics in the Pipeline
Friday, October 24, 2025
2:40 PM - 3:10 PM PDT