Jessica C. Petrov, MD, MSc1, Asrita Vattikonda, MD1, Aya Tamim, 2, Osayande Osagiede, MBBS, MPH3, Bhaumik Brahmbhatt, MBBS, MD1, Frank J. Lukens, MD1, Francis A.. Farraye, MD, MSc, MACG1, Hani Tamim, PhD4, Jana G. Hashash, MD, MSc, FACG1 1Mayo Clinic, Jacksonville, FL; 2College of Biological Science, University of Guelph, Guelph, ON, Canada; 3Mayo Clinic, Jacksonville, FL, US, Jacksonville, FL; 4American University of Beirut, Riad El Solh, Beyrouth, Lebanon Introduction: Incomplete bowel transit after video capsule endoscopy (VCE) placement is a common challenge in patients undergoing small bowel evaluation, especially amongst hospitalized patients. Our aims were to compare VCE completion rates between patients who underwent VCE as inpatients vs outpatients and identify patient related risk factors associated with incomplete studies. Methods: This was a single center, retrospective study of patients who underwent small bowel VCE at a tertiary referral center between 1/2022 and 6/2024. Baseline patient characteristics including demographics and medical history were collected. Details of capsule placement and recordings were also obtained. Continuous variables were summarized as mean (SD) and categorical variables were reported as frequency (%). Continuous variables were compared using independent t-test and categorical variables were compared using Chi-square test. Comparisons between inpatient and outpatient groups and then between complete vs incomplete studies were performed. Analysis was performed using SPSS-29 and p-values < 0.05 were considered statistically significant. Results: A total of 128 patients undergoing VCE were included: 63 inpatients and 65 outpatients. Table 1 compares patient baseline characteristics of inpatients and outpatients who underwent VCE. Both groups were comparable in terms of age, sex, BMI, ethnicity, and comorbid conditions. More outpatients were on GLP1 receptor agonists (RA) compared to inpatients (13.8% vs 1.6%, p=0.02) (Table 1). VCEs performed in the inpatient setting were more likely to be incomplete compared to outpatients (39.7% vs 12.3%, p < 0.001). Mean gastric transit time was longer for inpatients compared to outpatients (126.1 min ± SD 107.9) vs 39.1 min ±SD 49.2, p=0.03) (Table 2). Discussion: Inpatients have prolonged gastric transit times compared with outpatients which is associated with an increased rate of incomplete studies. This is despite more outpatients being on GLP1 RA. One strategy to consider for increasing completion rates is to administer 12-hour capsules for all inpatients and encourage ambulation when possible. Another approach would be to implement a standardized protocol where the capsule location is assessed early after capsule ingestion to ensure it has left the stomach. Future studies including a larger sample size are needed to understand additional characteristics associated with incomplete inpatient VCE studies.
Disclosures: Jessica Petrov indicated no relevant financial relationships. Asrita Vattikonda indicated no relevant financial relationships. Aya Tamim indicated no relevant financial relationships. Osayande Osagiede indicated no relevant financial relationships. Bhaumik Brahmbhatt indicated no relevant financial relationships. Frank Lukens indicated no relevant financial relationships. Francis Farraye: Astellas – Advisory Committee/Board Member. Avalo – Advisory Committee/Board Member. Bausch – Advisory Committee/Board Member. BMS – Advisory Committee/Board Member. Braintree Labs – Advisory Committee/Board Member. Fresenius Kabi – Advisory Committee/Board Member. GI Reviewers – Independent Contractor. IBD Educational Group – Independent Contractor. Iterative Health – Advisory Committee/Board Member, Stock Options. Janssen – Advisory Committee/Board Member. Lilly – DSMB. Pfizer – Advisory Committee/Board Member. Pharmacosmos – Advisory Committee/Board Member. Sandoz – Advisory Committee/Board Member. Viatris – Advisory Committee/Board Member. Hani Tamim indicated no relevant financial relationships. Jana Hashash: BMS – Ad Board.
Jessica C. Petrov, MD, MSc1, Asrita Vattikonda, MD1, Aya Tamim, 2, Osayande Osagiede, MBBS, MPH3, Bhaumik Brahmbhatt, MBBS, MD1, Frank J. Lukens, MD1, Francis A.. Farraye, MD, MSc, MACG1, Hani Tamim, PhD4, Jana G. Hashash, MD, MSc, FACG1. P4030 - Inpatient Video Capsule Endoscopy: Why the Incomplete Rates?, ACG 2025 Annual Scientific Meeting Abstracts. Phoenix, AZ: American College of Gastroenterology.
