Muhammad Kamal, MD1, Umar Hayat, MD2, Aamir Saeed, MD3, Vaniza Mehak, MD4, Zubair Khan, MD5, Abu Fahad Abbasi, MD6, Anudeep Deevi, BS7, Hassam Ali, MD8, Kishore Kumar, MD9, Karan J.. Yagnik, MD10, Danial H. Shaikh, MD11, Asad Ali, MD12, Faisal Kamal, MD13, Hafiz Muzaffar Akbar Khan, MD14, Ali Siddiqui, MD15 1Hackensack Meridian Health, Edison, NJ; 2Geisinger Wyoming Valley Medical Center, Wilkes-Barre, PA; 3Vanderbilt University Medical Center, Nashville, TN; 4RWJBarnabas Health, Trinitas Regional Medical Center, Roselle Park, NJ; 5Mercy Clinic East Communities, Festus, MO; 6Mercyhealth Gastroenterology Fellowship, Rockford, IL; 7Rowan-Virtua School of Osteopathic Medicine, Freehold, NJ; 8East Carolina University/Brody School of Medicine, Greenville, NC; 9Geisinger Commonwealth School of Medicine, Scranton, PA; 10Monmouth Medical Center, Robert Wood Johnson Medical School of Rutgers University, Long Branch, NJ; 11Geisinger Health System, Danville, PA; 12SUNY Upstate Medical University Hospital, Syracuse, NY; 13Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA; 14AdventHealth, Tampa, FL; 15Maimonides Medical Center, Fairfax, VA Introduction: Choledocholithiasis is common in elderly patients, yet cholecystectomy is often deferred due to perceived surgical risks. This study evaluates whether combining cholecystectomy with ERCP reduces 30-day readmissions in elderly patients with choledocholithiasis. Methods: A retrospective analysis of the 2021 National Readmission Database (NRD) included patients aged ≥65 with choledocholithiasis. Groups were stratified by ERCP alone versus ERCP plus cholecystectomy. Outcomes included 30-day readmission, mortality, and discharge disposition. Weighted analyses adjusted for confounders. Results: Among 28,424 patients, 18,188 underwent ERCP alone, and 10,236 had both procedures. The ERCP-only group was older (83.3 vs. 81.7 years, p < 0.001) and had more females (55.8% vs. 51.9%, p < 0.001). The 30-day readmission rate was higher in the ERCP-only group (10.0% vs. 6.4%, p < 0.0001), with higher mortality (2.9% vs. 1.1%, p < 0.0001). Adjusted analysis showed a 56.29% higher readmission risk without cholecystectomy (OR 1.5629, 95% CI 1.4242–1.7150, p < 0.0001). Discussion: Concurrent cholecystectomy with ERCP significantly reduces readmissions and mortality in elderly patients. These findings support integrating cholecystectomy into choledocholithiasis management for this population. Further research should optimize timing and assess long-term outcomes.
Figure: Table 1: a) Comparison of Patient and Hospital Characteristics
Disclosures: Muhammad Kamal indicated no relevant financial relationships. Umar Hayat indicated no relevant financial relationships. Aamir Saeed indicated no relevant financial relationships. Vaniza Mehak indicated no relevant financial relationships. Zubair Khan indicated no relevant financial relationships. Abu Fahad Abbasi indicated no relevant financial relationships. Anudeep Deevi indicated no relevant financial relationships. Hassam Ali indicated no relevant financial relationships. Kishore Kumar indicated no relevant financial relationships. Karan Yagnik indicated no relevant financial relationships. Danial Shaikh indicated no relevant financial relationships. Asad Ali indicated no relevant financial relationships. Faisal Kamal indicated no relevant financial relationships. Hafiz Muzaffar Akbar Khan indicated no relevant financial relationships. Ali Siddiqui indicated no relevant financial relationships.
Muhammad Kamal, MD1, Umar Hayat, MD2, Aamir Saeed, MD3, Vaniza Mehak, MD4, Zubair Khan, MD5, Abu Fahad Abbasi, MD6, Anudeep Deevi, BS7, Hassam Ali, MD8, Kishore Kumar, MD9, Karan J.. Yagnik, MD10, Danial H. Shaikh, MD11, Asad Ali, MD12, Faisal Kamal, MD13, Hafiz Muzaffar Akbar Khan, MD14, Ali Siddiqui, MD15. P3506 - Impact of Elective Cholecystectomy Following ERCP on Readmission Rates in Elderly Patients With Choledocholithiasis: A Nationwide Analysis, ACG 2025 Annual Scientific Meeting Abstracts. Phoenix, AZ: American College of Gastroenterology.
