P0343 - Cecal Outpouching on CT: Imaging-Guided Diagnosis and Urgent Colonoscopy in a Case of Suspected Cecal Diverticulitis

Cecal diverticulitis is a rare cause of right lower quadrant pain in Western populations and often mimics appendicitis. CT imaging is essential for accurate diagnosis and can help avoid unnecessary surgery. This case demonstrates how imaging guided the diagnosis and urgent colonoscopic evaluation of a suspected complicated cecal diverticulitis.


Case Description/

Methods:

A 48-year-old male with no significant past medical history presented with acute right lower quadrant abdominal pain and stable vital signs. Laboratory workup showed leukocytosis (WBC 12.3), elevated inflammatory markers (ESR 45, CRP 136), and fecal calprotectin of 604 µg/g. Initial CT abdomen/pelvis with IV contrast revealed a 4.5 cm debris-filled outpouching from the anterior cecum, with wall thickening and pericolonic fat stranding. Differential at the time  included acute right-sided diverticulitis versus contained perforation of a cecal mass. A follow-up CT with oral contrast confirmed similar findings, prompting urgent colonoscopy due to the concern for an evolving perforation and to obtain tissue diagnosis.

 


Colonoscopy showed purulent exudate and active extravasation at the cecal outpouching, correlating with CT findings.  The appendix was normal. Patient was started on antibiotics and Serial imaging showed improvement with lesion size decreasing to 2.1 × 2.4 cm, consistent with resolving localized diverticulitis or sealed perforation. The patient was managed conservatively with antibiotics and discharged in stable condition with outpatient GI follow-up.

Discussion:

Right-sided diverticulitis is uncommon in Western populations and often mimics acute appendicitis, frequently leading to unnecessary surgical intervention. In this case, CT imaging was instrumental in identifying a large inflammatory cecal outpouching with normal appendix, shifting the diagnostic focus away from appendicitis. This radiologic clarity enabled a conservative, non-surgical approach with antibiotics and close follow-up. Urgent colonoscopy, guided by imaging, confirmed the source of inflammation and excluded malignancy. This case highlights how early and accurate imaging can prevent unwarranted surgery by distinguishing diverticulitis from surgical mimics.




Figure: Diverticulitis


Figure: Pus oozing from cecal diverticula

Disclosures:
Jazza Jamil indicated no relevant financial relationships.
Ghazala Munawar indicated no relevant financial relationships.
Raehun Lee indicated no relevant financial relationships.
Pir Shah indicated no relevant financial relationships.
Navjot Singh indicated no relevant financial relationships.

Jazza Jamil, MBBS¹, Ghazala Munawar, MD², Raehun Lee, MD³, Pir Shah, MD⁴, Navjot Singh, MD³. P0343 - Cecal Outpouching on CT: Imaging-Guided Diagnosis and Urgent Colonoscopy in a Case of Suspected Cecal Diverticulitis, ACG 2025 Annual Scientific Meeting Abstracts. Phoenix, AZ: American College of Gastroenterology.