P0258 - No Improvement in Endoscopist Performance With Computer-Aided Colonoscopy in Real-World Community Settings

Pujan Kandel, MD¹, Vamsee Mupparaju, MD², Melvin Joy, MD³, Gnanashree Dharmarpandi, MD², Sreekanth Chandrupatla, MD²
1HCA Florida Citrus Memorial Hospital, Gainesville, FL; 2HCA Florida Healthcare Citrus Memorial hospital, Inverness, FL; 3HCA Healthcare Citrus Hospital, Inverness, FL

Introduction: Computer-aided detection (CADe) systems, such as GI Genius, have shown promise in improving adenoma detection rate (ADR) in controlled settings. However, the effectiveness of CADe in real-world, community-based colonoscopy practice remains unclear. This study aimed to evaluate whether CADe improves ADR and adenoma per colonoscopy (APC) in a community endoscopy center.

Methods: This was a retrospective cohort study at a single community medical center. Colonoscopies performed from April 2022 to April 2024 were reviewed using the GIQuIC database. GI Genius was implemented in mid-April 2023. Colonoscopies performed one year before installation (April 2022–April 2023; non-CADe group) were compared with those performed one year after installation (mid-April 2023–April 2024; CADe group). The primary outcome was ADR; secondary outcomes included APC and serrated lesion detection rate. Statistical analysis was performed using JMP v10.

Results: A total of 10,125 colonoscopies were included (non-CADe: 4,891; CADe: 5,233). Baseline demographics, bowel preparation quality (BBPS >2), and withdrawal times were similar between groups. Median insertion time was longer in the CADe group. ADR did not significantly differ: 55% in the non-CADe group vs. 56% in the CADe group (RR, 0.98; 95% CI, 0.88–1.22) Figure1. Serrated adenoma detection was also similar (13% vs. 14%, RR, 1.06; 95% CI, 0.85–1.46). However, advanced adenoma detection was higher in the CADe group Figure 2.

Discussion:

In this real-world community setting, CADe-assisted colonoscopy did not significantly improve ADR or serrated lesion detection. The clinical utility of CADe systems outside academic centers remains uncertain and warrants further prospective investigation.


Figure: Figure 1


Figure: Figure 2

Disclosures:
Pujan Kandel indicated no relevant financial relationships.
Vamsee Mupparaju indicated no relevant financial relationships.
Melvin Joy indicated no relevant financial relationships.
Gnanashree Dharmarpandi indicated no relevant financial relationships.
Sreekanth Chandrupatla indicated no relevant financial relationships.

Pujan Kandel, MD¹, Vamsee Mupparaju, MD², Melvin Joy, MD³, Gnanashree Dharmarpandi, MD², Sreekanth Chandrupatla, MD². P0258 - No Improvement in Endoscopist Performance With Computer-Aided Colonoscopy in Real-World Community Settings, ACG 2025 Annual Scientific Meeting Abstracts. Phoenix, AZ: American College of Gastroenterology.